Anti-TREM2, AlpHcAbs® Human antibody

Details and Advantages
Applications: ELISA,Flow Cyt
Reactivity: Human
Conjugate: Unconjugated
Advantages:

High lot-to-lot consistency

Increased sensitivity and higher affinity

Animal-free production

Summary >
Description:
Anti-TREM2, AlpHcAbs® Human antibody is designed for detecting human TREM2 specifically. Based on ELISA and/or FCM, Anti-TREM2, AlpHcAbs® Human antibody reacts with human TREM2 specifically.

Immunogen: Recombinant human TREM2
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human TREM2
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Performance >
ELISA: 1:4,000-1:10000
Flow Cytometry:1:200-1:1000

Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.