· Consistent and reproducible results;
· Extraordinarybinding,even under harsh conditions;
· High affinity and Short incubation (5-30min)
Description:
Human IgG Nanoselector Magnetic beads have been specifically designed to bind human IgG. Human IgG Nanoselector Magnetic beads is based on small high-affinity recombinant alpaca antibody fragments covalently coupled to the surface of Magnetic beads. Human IgG Nanoselector Magnetic beads is an ideal tool to isolate or purify human IgG or human IgG Fc-fusion proteins fast and efficiently.
Ligand: Anti-human IgG Fc single domain antibody fragment (VHH, Nanobody)
Bead size: ~ 2.8µm
Reactivity: Highly selective for human IgG Fc, no binding to rabbit, mouse, bovine, horse, sheep and goat IgG.
Binding Capacity: High binding capacity, 10 µL slurry bind about 100 µg of recombinant human IgG.
Storage: Shipped at ambient temperature. Upon receipt store at 4°C. Stable for 1 year. Do not freeze.
Storage Buffer: 50 % slurry in PBS containing 20 % Ethanol
Background:
Human IgG Nanoselector Magnetic beads has been specifically designed to bind human IgG Fc. The ligand on the resin is Anti-human IgG Fc single domain antibody fragment(VHH), which is single-domain antibody derived from the variable regions of heavy chain of Camelidae immunoglobulin, also called SdAbs. Compared with protein A/G, Human IgG Nanoselector Magnetic beads has much higher affinity than protein A/G. Human IgG Nanoselector Magnetic beads is effective to pull down human IgG, and 10 µL slurry bind about 100 µg of human IgG.
Protein purification
Immunoprecipitation (IP)/Co-IP
Mass spectrometry (MS)
